RHEUMATIC FEVER

 ACUTE RHEUMATIC FEVER-MCQS

CLINICAL MANIFESTATION OF ACUTE RHEUMATIC FEVER INCLUDES

1. SUBCUTANEOUS NODULES-
2.CARDITIS-
3.CHOREA
4.JOINT PAINS
5.ERYTEMA MARGINATUM

1. TRUE-rare but highly specific -seen as painless nodules in bony prominence
2. TRUE-a pancarditis-manifestation depend on the degree of heart involvement .
3. FALSE-Sydenham chorea-common in females-manifest after a long latency period of months .
4. TRUE-ARTHRITIS/POLYARTHRALGIA-usually seen within 21 days of infection- a major manifestation.
5. TRUE-rare but highly specific manifestation-may be seen after a hot shower.
ALL THESE CALLED MAJOR MANIFESTATIONS.

SPINAL MUSCULAR DYSTROPHY -MCQS

 SPINAL MUSCULAR DYSTROPHY -MCQS

RED FLAGS SIGNS OF SPINAL MUSCULAR DYSTROPHY INCLUDES

1.Hypotonia.
2.No head control.
3.Absent reflexes.
4.Tounge fasciculation.
5.Cognitive impairment.

ANSWERS
1.TRUE-Profound hypotonia
2.TRUE-Little or no head control
3.TRUE-Absent ,reduced or asymmetric moro reflex and deep tendon reflexes
4.TRUE-feeding difficulty, recurrent respiratory tract infections.
5.FALSE-Normal cognitive development(baby is happy and bright but lazy!)

THYROIDITIS

 

DRUG INDUCED THYROIDITIS-MCQS

 

1.Tyrosine kinase inhibitors are associated with thyroid dysfunction.

2.Alemtuzumab(Lemtrada) is associated with thyroid dysfunction.

3.Immune checkpoint inhibitors are associated with thyroid dysfunction.

4.Amiodarone contains about 68% by weight of iodine.

5.Lithium associated thyroid dysfunction is commonly seen few weeks after commencing treatment.

 

 

ANSWERS

1.    TRUE-

2.    TRUE-used to treat multiple sclerosis

3.    TRUE-are monoclonal antibodies

4.    TRUE

5.    FALSE-generally occurring after 8-12 months of treatment.

HASHIMOTOS THYROIDITIS

 

HASHIMOTOS THYROIDIITS-MCQS

 

1.Is thought to be of autoimmune origin with lymphocytic infiltration of the thyroid gland .

2.Is associated with the presence of TPO(thyroid peroxidase )antibodies in most cases.

3. Episodes of thyroiditis occur  particularly during post partum period.

4. Family history of autoimmune thyroid disease is a clue to diagnosis.

5. A classic triphasic pattern of hyperthyroidism ,hypothyroidism and return to euthyroidism is well recognised.

 

ANSWERS

1.    TRUE-exact pathophysiology remains unclear

2.    TRUE- more than 90% of cases

3.    TRUE- but can present at any other time .

4.    TRUE- and/or personal history of autoimmune disease.

5.      TRUE- Correlation of the disease with TPO antibody titre is unclear.

HASHIMOTOS  THYROIDITIS-MCQS

1. Recurrent postpartum thyroiditis is common in subsequent pregnancies
2. The initial hyperthyroid phase can easily be missed clinically.
3. Hypothyroid state is more commonly seen in clinical practice
4. Hypothyroidism is usually insidious in onset and may be progressing over years.
5. Is the most common cause of hypothyroidism in iodine insufficient areas of the world

ANSWERS
1. TURE-more than 75%
2. TRUE
3. TRUE
4. TRUE-Need monitoring
5. TRUE-